ITGA5 anticorps

N° du produit ABIN7115337

Cet anticorps anti-ITGA5 est un anticorps Lapin Polyclonal détectant ITGA5 dans WB et ELISA. Adapté pour Humain, Souris, Rat et Singe.

Aperçu rapide pour ITGA5 anticorps (ABIN7115337)

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ITGA5 anticorps

Fonction: ITGA5 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: integrin, alpha 5

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ITGA5

Antigène: ITGA5 (Integrin, alpha 5 (ITGA5))

Autre désignation: ITGA5

Sujet:

Synonyms: Integrin alpha-5|CD49 antigen-like family member E|Fibronectin receptor subunit alpha|Integrin alpha-F|VLA-5|Integrin alpha-5 heavy chain|Integrin alpha-5 light chain|ITGA5|FNRA

Background: Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).

Poids moléculaire: 120 kDa

UniProt: P08648

Pathways: Integrin Complex